Zobrazit minimální záznam
dc.contributor.author |
Abdel-Razeq, Sawsan A. |
|
dc.contributor.author |
Foaud, Manal M. |
|
dc.contributor.author |
Salama, Nahla N. |
|
dc.contributor.author |
Abdel-Atty, Shimaa |
|
dc.contributor.author |
El-Kosy, Naglaa |
|
dc.date.accessioned |
2012-03-07T07:28:56Z |
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dc.date.available |
2012-03-07T07:28:56Z |
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dc.date.issued |
2011 |
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dc.identifier.isbn |
978-80-7395-434-5 (printed) |
|
dc.identifier.isbn |
978-80-7395-435-2 (on-line) |
|
dc.identifier.uri |
http://hdl.handle.net/10195/42515 |
|
dc.description.abstract |
The electrochemical behavior of the two antihistaminic drugs Azelastine-HCl and
Emedastine difumarate is studied in micellar solutions. Anodic oxidation is obtained at the glassy carbon electrode (GCE) and a carbon paste electrode (CPE) using cyclic voltammetry(CV) and differential pulse voltammetry (DPV) in Britton-Robinson buffers (pH 8 and pH 6) containing 0.8×10-4 M sodium dodecylsulphate (SDS). The peak potential shifts to more positive value in anionic surfactant (sodium dodecylsulphate solution) than in presence of cationic surfactant (cetyltrimethylammonium bromide) or the non-ionic surfactant (Triton
X-100). The oxidation was characterized by the single one-electron wave. The method has been validated according to the ICH Guidelines, when the limit of quantitation ranges between 0.4×10-7 and 0.8×10-7 mol L-1. |
cze |
dc.format |
p. 289-306 |
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dc.language.iso |
eng |
|
dc.publisher |
Univerzita Pardubice |
cze |
dc.relation.ispartof |
Sensing in electroanalysis. K. Kalcher, R. Metelka, I. Švancara, K. Vytřas (Eds.).2011, Volume 6. |
|
dc.rights |
open access |
|
dc.subject |
electrochemistry |
cze |
dc.subject |
glassy carbon electrode |
cze |
dc.subject |
carbon paste electrode |
cze |
dc.subject |
surfactants |
cze |
dc.subject |
Azelastine-HCl |
cze |
dc.subject |
emedastine difumarate |
cze |
dc.subject |
determination |
cze |
dc.subject |
pharmaceuticals |
cze |
dc.title |
Voltammetric determination of Azelastine-HCl and Emedastine dirumarate in micellar solution at glassy carbon and carbon paste electrodes |
cze |
dc.type |
Article |
cze |
dc.peerreviewed |
yes |
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dc.publicationstatus |
published |
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