16 (2010) Scientific papers, Series Ahttps://hdl.handle.net/10195/424802024-03-29T01:24:18Z2024-03-29T01:24:18ZNew type of PVC-membrane Ion-selective electrodes and their applicability to determine some antidepressand drugsWassel, Anwar A.Abdullatif, Shabaanhttps://hdl.handle.net/10195/426402012-07-03T11:25:03Z2010-01-01T00:00:00ZNew type of PVC-membrane Ion-selective electrodes and their applicability to determine some antidepressand drugs
Wassel, Anwar A.; Abdullatif, Shabaan
The construction and electrochemical characterisation of potentiometric sensors of the PVC-membrane type are described being developed for the determination of selected antidepressants; namely: Olanzapine, Oxazepam, and Lorazepam. The sensing PVC-membranes incorporate the ion-associates of the drug cations with ammonium reineckate as selective materials dispersed in 2-nitrophenyl-octylether
(NPOE) or dibutyl sebacate (DBS) as the plasticizers of choice. These ISEs exhibit
rapid, stable and nearly Nernstian response over a relatively wide concentration range of 1×10–7 mol l–1-0.01 mol l–1 for Olanzapine and 1×10–6-0.01 mol l–1 for Oxazepam and Lorazepam, in mild acidic solutions with pH 4.5. No interferences caused by either inorganic or organic species were found. The three electrodes
developed have been tested for potentiometric titrations of all three drugs, as well
as for their direct determination via the respective calibration curves. The
individual experiments then resulted in average recovery rates in an interval of
34 Wassel A.A., Abdullatif S./Sci. Pap. Univ. Pardubice Ser. A 16 (2010) 33–55
98.4-99.2 %, with the R.S.D. of ca. ±1.5 % (n = 3) for all three analytes of interest.
Finally, the method proposed has been applied to the determination of the three
drugs in pharmaceutical formulations and urine, when the results obtained were comparable to those obtained with the reference HPLC measurements.
2010-01-01T00:00:00ZTriple helix model in the Czech tertiary educationSabolová, Veronikahttps://hdl.handle.net/10195/426392012-07-03T11:25:07Z2010-01-01T00:00:00ZTriple helix model in the Czech tertiary education
Sabolová, Veronika
The article is devoted to the issue of triple helix model and its application in the Czech tertiary education. Introduction describes the crucial provisions of the White Paper on Tertiary Education. Then the triple helix model is described based on the foreign literature search. Particular attention is focused on the importance
of the triple helix model in the White Paper on Tertiary Education. Finally, possible subjects of the cooperation between university, industry and government are indicated.
2010-01-01T00:00:00ZTime series forecasting as a tool of operative managementPaták, MichalVlčková, Vladimírahttps://hdl.handle.net/10195/426382012-07-03T11:25:08Z2010-01-01T00:00:00ZTime series forecasting as a tool of operative management
Paták, Michal; Vlčková, Vladimíra
Present quickly varying business environment requires changes in traditional logistic management of companies of chemical and food industry operating on B2C markets. Usage of recent logistic technologies however is made impossible due to the position of Czech companies on the markets mentioned. This article presents the problems which these companies solve on the operative level, and points out possibilities of time series analysis utilization as a tool of demand planning. Possible application of this tool in operative management and its incidences are described on a chosen company of food industry.
2010-01-01T00:00:00ZAnticorrosion properties of ion-exchangable pigments in epoxide coatingsObrdlík, ŠtěpánKalendová, AndreaMatějková, Evahttps://hdl.handle.net/10195/426372012-07-03T11:25:05Z2010-01-01T00:00:00ZAnticorrosion properties of ion-exchangable pigments in epoxide coatings
Obrdlík, Štěpán; Kalendová, Andrea; Matějková, Eva
Hexavalent chromium compounds (chromates) have been widely used as inhibitive pigments in the formulation of anticorrosive paints. However, their high toxicity and carcinogenic effects are forcing the development of effective chromate-free
organic coatings. One such alternative, which is very attractive from a scientific point of view, is the use of ion-exchangeable pigments (IEPs). The few studies conducted with this type of pigment are not conclusive about their anticorrosive efficiency and controversy surrounds their functioning mechanisms, interchange capacity and anticorrosive performance. In the present research, which focuses on the anticorrosive protection of this type of pigment, calcium/silica (Ca/Si) IEPs
were synthesized in first step, next epoxide paint coatings were formulated. IEPs have been applied on low carbon steel panels. The effect of these non-toxic pigments on the protective properties of coatings has been tested by means of
natural and accelerated corrosion tests (humidity, salt spray and SO2). Experimental results have shown that IEPs are suitable to formulate anticorrosive paint films with improved anticorrosive effects.
2010-01-01T00:00:00Z